rs2425025

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

suntan

Visconti A et al. “Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.” Nature Communications 9(1):1684 (2018)

Allele G

OR 0.50

p 4.0e-253

N 121,296

Large GWAS

European

melanoma

Rashkin SR et al. “Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts.” Nature Communications 11(1):4423 (2020)

Allele G

OR 1.38

p 4.0e-28

N 417,127

Large GWAS

European

actinic keratosis

Kim Y et al. “Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways.” Communications Biology 5(1):386 (2022)

Allele G

OR 1.27

p 7.0e-25

N 92,240

Large GWAS

European

non-melanoma skin carcinoma

Visconti A et al. “Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.” Nature Communications 9(1):1684 (2018)

Allele A

OR 1.25

p 7.0e-13

N 187,652

Large GWAS

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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