Trait
SNPs associated with Actinic keratosis
46 genetic variants across 23 genes have been associated with Actinic keratosis in published research. Key genes include ATP11A, BRCA2, CTLA4.
Associated variants46 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12203592 | IRF4 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs16891982 | SLC45A2 | GWAS association (p=2.0e-311) | Major Consortium Study |
| rs6059655 | RALY | GWAS association (p=1.0e-218) | Major Consortium Study |
| rs1126809 | TYR | GWAS association (p=4.0e-171) | Major Consortium Study |
| rs62211989 | — | GWAS association (p=7.0e-125) | Major Consortium Study |
| rs12350739 | — | GWAS association (p=1.0e-95) | Major Consortium Study |
| rs6791479 | — | GWAS association (p=1.0e-40) | Major Consortium Study |
| rs117744081 | — | GWAS association (p=3.0e-28) | Major Consortium Study |
| rs12126004 | LOC107985204 | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs2737206 | — | GWAS association (p=3.0e-23) | Major Consortium Study |
| rs72928978 | TPCN2 | GWAS association (p=6.0e-23) | Major Consortium Study |
| rs11571818 | BRCA2 | GWAS association (p=3.0e-22) | Major Consortium Study |
| rs7742789 | — | GWAS association (p=8.0e-22) | Major Consortium Study |
| rs117132860 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs6007506 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs11611584 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs9549317 | ATP11A | GWAS association (p=4.0e-20) | Major Consortium Study |
| rs7939541 | — | GWAS association (p=6.0e-20) | Major Consortium Study |
| rs9274619 | HLA-DQB1 | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs182533474 | JAZF1 | GWAS association (p=6.0e-19) | Major Consortium Study |
| rs759382 | — | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs9836630 | FOXP1 | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs13079741 | — | GWAS association (p=2.0e-18) | Major Consortium Study |
| rs3087243 | CTLA4 | GWAS association (p=9.0e-18) | Major Consortium Study |
| rs9265640 | — | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs78378222 | TP53 | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs12123821 | — | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs62280667 | — | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs705705 | RPS26 | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs17513531 | — | GWAS association (p=8.0e-15) | Major Consortium Study |
| rs56200417 | MDM4 | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs1667392 | HERC2 | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs6679677 | PHTF1 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs1214761 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs61893460 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs12372954 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs374837794 | SCHLAP1 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs1426654 | SLC24A5 | GWAS association (p=8.0e-37) | Major Consortium Study |
| rs1805007 | MC1R | GWAS association (p=4.0e-319) | Major Consortium Study |
| rs4268748 | DEF8 | GWAS association (p=2.0e-61) | Large GWAS |
| rs2425025 | — | GWAS association (p=7.0e-25) | Large GWAS |
| rs12916300 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs7638354 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs4455710 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs35063026 | SPATA33 | GWAS association (p=7.0e-11) | Large GWAS |
| rs7832568 | TRPS1 | GWAS association (p=3.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.