rs62211989

GWAS Catalog Trait Associations (10)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

actinic keratosis

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.28
p 7.0e-125
N 590,789
Major Consortium StudyLarge GWAS
multi-ancestry

skin disease

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.20
p 9.0e-119
N 397,744
Major Consortium StudyLarge GWAS
European

skin neoplasm

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.25
p 4.0e-85
N 569,832
Major Consortium StudyLarge GWAS
multi-ancestry

squamous cell carcinoma

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.29
p 5.0e-57
N 438,891
Major Consortium StudyLarge GWAS
European

phototoxic dermatitis

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.25
p 1.0e-28
N 430,978
Major Consortium StudyLarge GWAS
European

family history of cancer

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.17
p 2.0e-20
N 400,487
Major Consortium StudyLarge GWAS
multi-ancestry

aging rate

Roberts V et al. Genome-Wide Association Study Identifies Genetic Associations with Perceived Age. The Journal of Investigative Dermatology 140(12):2380-2385 (2020)
Allele G
OR 1.06
p 3.0e-14
N 423,992
Large GWAS
European

appendicular lean mass

Hernandez Cordero AI et al. Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. American Journal of Human Genetics 105(6):1222-1236 (2019)
Allele C
OR 0.09
p 3.0e-13
N 181,862
Large GWAS
European

drug use measurement, skin cancer

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.26
p 4.0e-15
N 371,173
Major Consortium StudyLarge GWAS
multi-ancestry

skin cancer

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.29
p 2.0e-99
N 400,487
Major Consortium StudyLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…