rs10739221
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
age at menarche
Perry JR et al. “Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.” Nature 514(7520):92-97 (2014)
Allele C
OR 0.08
p 4.0e-41
N 182,413
Large GWAS
European
cutaneous melanoma
Liyanage UE et al. “Multi-Trait Genetic Analysis Identifies Autoimmune Loci Associated with Cutaneous Melanoma.” The Journal of Investigative Dermatology 142(6):1607-1616 (2022)
Allele T
OR 0.07
p 5.0e-20
N 380,287
Large GWAS
European
Law MH et al. “Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.” Nature Genetics 47(9):987-995 (2015)
Allele T
OR 0.12
p 7.0e-11
N 36,077
Meta-analysisLarge GWAS
European
melanoma
Ransohoff KJ et al. “Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.” Oncotarget 8(11):17586-17592 (2017)
Allele T
OR 1.13
p 7.0e-11
N 291,407
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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