Trait
SNPs associated with Cutaneous melanoma
132 genetic variants across 45 genes have been associated with Cutaneous melanoma in published research. Key genes include ADGRV1, AKAP12, AP4B1.
Associated variants132 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1805008 | MC1R | Increased cutaneous melanoma risk | Meta-analysis |
| rs10739221 | — | GWAS association (p=5.0e-20) | Meta-analysis |
| rs6914598 | — | GWAS association (p=1.0e-18) | Meta-analysis |
| rs498136 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs2995264 | STN1 | GWAS association (p=2.0e-09) | Meta-analysis |
| rs6750047 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs1636744 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs1805009 | MC1R | Increased cutaneous melanoma risk | Meta-analysis |
| rs12203592 | IRF4 | GWAS association (p=2.0e-298) | Major Consortium Study |
| rs1805007 | MC1R | GWAS association (p=1.0e-288) | Major Consortium Study |
| rs6059655 | RALY | GWAS association (p=3.0e-157) | Major Consortium Study |
| rs1126809 | TYR | GWAS association (p=3.0e-114) | Major Consortium Study |
| rs935055 | MTAP | GWAS association (p=2.0e-47) | Major Consortium Study |
| rs10197246 | — | GWAS association (p=9.0e-39) | Major Consortium Study |
| rs10810650 | — | GWAS association (p=9.0e-33) | Major Consortium Study |
| rs72928038 | — | GWAS association (p=5.0e-27) | Major Consortium Study |
| rs11170164 | KRT5 | GWAS association (p=4.0e-25) | Major Consortium Study |
| rs117744081 | — | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs452384 | — | GWAS association (p=4.0e-22) | Major Consortium Study |
| rs62244884 | — | GWAS association (p=8.0e-22) | Major Consortium Study |
| rs117132860 | — | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs214787 | TGM3 | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs140691474 | CTSS | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs4384 | — | GWAS association (p=4.0e-19) | Major Consortium Study |
| rs9271499 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs214758 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs2030519 | — | GWAS association (p=6.0e-17) | Major Consortium Study |
| rs3087243 | CTLA4 | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs1800440 | CYP1B1 | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs1426654 | SLC24A5 | GWAS association (p=5.0e-16) | Major Consortium Study |
| rs869330 | — | GWAS association (p=7.0e-16) | Major Consortium Study |
| rs6881722 | — | GWAS association (p=9.0e-16) | Major Consortium Study |
| rs204295 | — | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs4920607 | RCC2 | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs10424978 | — | GWAS association (p=9.0e-14) | Major Consortium Study |
| rs2072112 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs28506112 | LINC02291 | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs572318816 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs139761953 | PRKG1 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs5766576 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs56300457 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs10816595 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs11571818 | BRCA2 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs7508601 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs2476601 | PTPN22 | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs78378222 | TP53 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs149617956 | MITF | GWAS association (p=7.0e-33) | Major Consortium Study |
| rs16891982 | SLC45A2 | GWAS association (p=2.0e-141) | Major Consortium Study |
| rs121918166 | OCA2 | GWAS association (p=8.0e-18) | Major Consortium Study |
| rs871024 | — | GWAS association (p=2.0e-104) | Large GWAS |
| rs7943603 | — | GWAS association (p=4.0e-54) | Large GWAS |
| rs13178866 | CLPTM1L | GWAS association (p=1.0e-43) | Large GWAS |
| rs9929606 | — | GWAS association (p=2.0e-40) | Large GWAS |
| rs4911412 | — | GWAS association (p=2.0e-38) | Large GWAS |
| rs31490 | CLPTM1L | GWAS association (p=3.0e-36) | Large GWAS |
| rs132941 | — | GWAS association (p=3.0e-34) | Large GWAS |
| rs408825 | — | GWAS association (p=1.0e-32) | Large GWAS |
| rs7902587 | — | GWAS association (p=7.0e-32) | Large GWAS |
| rs1888621 | — | GWAS association (p=7.0e-31) | Large GWAS |
| rs76798800 | — | GWAS association (p=1.0e-26) | Large GWAS |
| rs12659201 | ADGRV1 | GWAS association (p=7.0e-23) | Large GWAS |
| rs12410050 | LOC107985204 | GWAS association (p=3.0e-22) | Large GWAS |
| rs3217986 | CDKN2B | GWAS association (p=4.0e-22) | Large GWAS |
| rs1801516 | ATM | GWAS association (p=2.0e-21) | Large GWAS |
| rs2695237 | — | GWAS association (p=4.0e-21) | Large GWAS |
| rs4354713 | — | GWAS association (p=9.0e-21) | Large GWAS |
| rs55797833 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs1339759 | — | GWAS association (p=6.0e-19) | Large GWAS |
| rs10936599 | MYNN | GWAS association (p=8.0e-19) | Large GWAS |
| rs10739220 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs13177787 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs7803075 | — | GWAS association (p=5.0e-17) | Large GWAS |
| rs32578 | — | GWAS association (p=7.0e-17) | Large GWAS |
| rs251465 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs4731207 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs11625064 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs2762461 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs1056927 | — | GWAS association (p=8.0e-15) | Large GWAS |
| rs190948281 | SAMMSON | GWAS association (p=2.0e-14) | Large GWAS |
| rs7705526 | TERT | GWAS association (p=2.0e-14) | Large GWAS |
| rs112761681 | MED13L | GWAS association (p=2.0e-14) | Large GWAS |
| rs73008229 | ATM | GWAS association (p=3.0e-14) | Large GWAS |
| rs8444 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs150962800 | FMN1 | GWAS association (p=5.0e-14) | Large GWAS |
| rs4420522 | CDH1 | GWAS association (p=8.0e-14) | Large GWAS |
| rs1481853 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs12597188 | CDH1 | GWAS association (p=3.0e-13) | Large GWAS |
| rs1278761 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs62034121 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs143190905 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs75883022 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs116927526 | — | GWAS association (p=8.0e-13) | Large GWAS |
| rs79356439 | CDKN2B-AS1 | GWAS association (p=9.0e-13) | Large GWAS |
| rs13263376 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs72834823 | LINC03005 | GWAS association (p=1.0e-12) | Large GWAS |
| rs5766565 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs12523094 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs10931936 | CASP8 | GWAS association (p=2.0e-12) | Large GWAS |
| rs10960710 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs9322309 | AKAP12 | GWAS association (p=3.0e-12) | Large GWAS |
Showing the top 100 of 132 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.