rs2456973
This is a intron variant variant in the IKZF4 gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
self reported educational attainment
Okbay A et al. “Genome-wide association study identifies 74 loci associated with educational attainment.” Nature 533(7604):539-42 (2016)
Allele A
OR —
β 0.019
p 6.0e-16
N 405,072
Large GWAS
European
Vitiligo
Jin Y et al. “Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.” Nature Genetics 44(6):676-80 (2012)
Allele C
OR 1.29
p 3.0e-14
N 3,228
Large GWAS
European
Alzheimer disease, educational attainment
Kulminski AM et al. “Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.” Geroscience 44(1):265-280 (2022)
Allele A
OR 56.38
p 2.0e-11
N 4,029
Large GWAS
eosinophil count
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.03
p 3.0e-14
N 447,366
Major Consortium StudyLarge GWAS
multi-ancestry
About IKZF4
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]
View all IKZF4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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