rs246185

This is a regulatory region variant variant in the MIR193BHG gene.

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

age at menarche

Perry JR et al. “Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.” Nature 514(7520):92-97 (2014)
Allele C
OR 0.04
p 7.0e-16
N 182,413
Large GWAS
European

QT interval

Arking DE et al. “Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.” Nature Genetics 46(8):826-36 (2014)
Allele C
OR 0.72
p 3.0e-13
N 71,061
Large GWAS
European

balding measurement

Heilmann-Heimbach S et al. “Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness.” Nature Communications 8:14694 (2017)
Allele T
OR 0.14
p 3.0e-10
N 22,518
Meta-analysisLarge GWAS
European

BMI-adjusted hip circumference

Christakoudi S et al. “GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.” Scientific Reports 11(1):10688 (2021)
Allele C
OR 0.02
p 2.0e-9
N 186,825
Major Consortium StudyLarge GWAS
European

puberty onset measurement

Cousminer DL et al. “Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.” Human Molecular Genetics 23(16):4452-64 (2014)
Allele T
OR 0.14
p 9.0e-9
N 3,769
Large GWAS
European

body height

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele C
OR 0.02
p 3.0e-87
N 928,679
Large GWAS
multi-ancestry
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele C
OR 0.02
p 3.0e-42
N 405,540
Large GWAS
European
Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele C
OR 0.02
p 1.0e-10
N 293,593
Large GWAS
African unspecified

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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