rs2486992605
This variant is located in the RHOBTB2 gene.
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitter1 publicationAbout RHOBTB2
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
View all RHOBTB2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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