rs2502437590
This variant is located in the SLC25A21 gene.
▶ClinVar annotation
Uncertain Significance★☆☆☆
1 submitter3 publicationsAbout SLC25A21
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]
View all SLC25A21 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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