rs2517873

This is a regulatory region variant variant.

▶

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

non-small cell lung carcinoma

Qin N et al. “Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.” Frontiers of Medicine 15(2):275-291 (2021)

Allele A

OR 1.16

p 5.0e-11

N 54,475

Large GWAS

multi-ancestry

Dai J et al. “Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.” The Lancet. Respiratory Medicine 7(10):881-891 (2019)

Allele A

OR 1.16

p 5.0e-11

N 54,475

Large GWAS

multi-ancestry

squamous cell lung carcinoma

Qin N et al. “Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.” Frontiers of Medicine 15(2):275-291 (2021)

Allele A

OR 1.23

p 2.0e-10

N 35,705

Large GWAS

East Asian, European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…