rs2545801
This is a upstream gene variant variant.
▶GWAS Catalog Trait Associations (16)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (16)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
phenylalanine measurement
Karjalainen MK et al. “Genome-wide characterization of circulating metabolic biomarkers.” Nature 628(8006):130-138 (2024)
Allele T
OR 0.09
p 5.0e-88
N 136,016
Large GWAS
multi-ancestry
blood coagulation trait
Tang W et al. “Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.” American Journal of Human Genetics 91(1):152-62 (2012)
Allele C
OR 1.68
p 6.0e-88
N 9,240
Large GWAS
European
superoxide dismutase [Mn], mitochondrial measurement
Suhre K et al. “Connecting genetic risk to disease end points through the human blood plasma proteome.” Nature Communications 8:14357 (2017)
Allele T
OR 0.61
p 5.0e-36
N 997
Small GWAS
multi-ancestry
histidine measurement
Lotta LA et al. “A cross-platform approach identifies genetic regulators of human metabolism and health.” Nature Genetics 53(1):54-64 (2021)
Allele C
OR 12.36
p 4.0e-35
N 80,809
Large GWAS
European
a disintegrin and metalloproteinase with thrombospondin motifs 15 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.07
p 3.0e-29
N 47,745
Large GWAS
European
CD63 antigen measurement
Allele C
OR 0.25
p 6.0e-19
N 3,301
Large GWAS
European
blood protein amount
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele T
OR 0.19
p 2.0e-17
N 5,368
Large GWAS
European
level of BAG family molecular chaperone regulator 3 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.05
p 4.0e-16
N 47,745
Large GWAS
European
prolylproline measurement
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele C
OR 0.23
p 3.0e-15
N 6,136
Large GWAS
European
free cholesterol to total lipids in large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 2.0e-14
N 450,015
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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