rs2653414
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 1.90
p 7.0e-297
N 10,708
Large GWAS
European
semaphorin-3G measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.27
p 7.0e-33
N 47,745
Large GWAS
European
colipase measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.21
p 2.0e-20
N 47,745
Large GWAS
European
lactotransferrin measurement
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele A
OR 0.46
p 1.0e-11
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
preeclampsia
Honigberg MC et al. “Polygenic prediction of preeclampsia and gestational hypertension.” Nature Medicine 29(6):1540-1549 (2023)
Allele A
OR 1.36
p 3.0e-11
N 455,887
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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