rs268134

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

educational attainment

Okbay A et al. “Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.” Nature Genetics 54(4):437-449 (2022)

Allele A

OR 0.01

p 1.0e-14

N 3,037,499

Large GWAS

European

systemic lupus erythematosus

Bentham J et al. “Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.” Nature Genetics 47(12):1457-1464 (2015)

Allele G

OR 1.21

p 1.0e-10

N 14,267

Large GWAS

European

Alzheimer disease, educational attainment

Kulminski AM et al. “Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.” Geroscience 44(1):265-280 (2022)

Allele A

OR 40.97

p 3.0e-8

N 4,029

Large GWAS

self reported educational attainment

Okbay A et al. “Genome-wide association study identifies 74 loci associated with educational attainment.” Nature 533(7604):539-42 (2016)

Allele A

OR —

β 0.014

p 4.0e-8

N 405,072

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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