rs2696423

This is a downstream gene variant variant in the LRRC37A gene.

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

hypothyroidism

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.10
p 1.0e-36
N 441,274
Major Consortium StudyLarge GWAS
European

blood sodium bicarbonate amount

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.03
p 9.0e-17
N 412,277
Major Consortium StudyLarge GWAS
European

About LRRC37A

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all LRRC37A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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