rs2792990
This is a intron variant variant in the RC3H2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
insomnia
Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele C
OR 0.01
p 2.0e-23
N 2,365,010
Meta-analysisLarge GWAS
European
insomnia measurement
Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele C
OR 1.06
p 1.0e-10
N 1,331,010
Large GWAS
European
About RC3H2
Enables DNA binding activity; RNA binding activity; and ubiquitin protein ligase activity. Involved in protein polyubiquitination. Located in cell surface; intracellular membrane-bounded organelle; and membrane. [provided by Alliance of Genome Resources, Apr 2025]
View all RC3H2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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