RC3H2
ring finger and CCCH-type domains 2
Summary
Enables DNA binding activity; RNA binding activity; and ubiquitin protein ligase activity. Involved in protein polyubiquitination. Located in cell surface; intracellular membrane-bounded organelle; and membrane. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants42 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1230171187 | 9:125,611,970 | A/C | — | uncertain significance |
| rs377349398 | 9:125,611,973 | T/G | — | uncertain significance |
| rs1588045614 | 9:125,612,073 | T/C | — | uncertain significance |
| rs764724224 | 9:125,612,078 | G/C | — | uncertain significance |
| rs4838018 | 9:125,612,807 | C/G | — | — |
| rs371837514 | 9:125,613,432 | T/G | — | uncertain significance |
| rs558832446 | 9:125,613,684 | T/C | — | uncertain significance |
| rs57140227 | 9:125,614,617 | T/C | intron variant | — |
| rs2538175892 | 9:125,616,335 | C/T | — | uncertain significance |
| rs776108258 | 9:125,616,540 | C/T | — | uncertain significance |
| rs141237981 | 9:125,617,668 | G/C | — | uncertain significance |
| rs2538181150 | 9:125,618,052 | C/T | — | uncertain significance |
| rs1382365185 | 9:125,618,145 | C/T | — | uncertain significance |
| rs368828068 | 9:125,620,209 | C/T | — | uncertain significance |
| rs943414589 | 9:125,620,221 | C/T | — | uncertain significance |
| rs377288600 | 9:125,620,305 | T/C | — | uncertain significance |
| rs776057339 | 9:125,620,991 | C/T | — | uncertain significance |
| rs374047636 | 9:125,621,000 | G/A | — | uncertain significance |
| rs548675904 | 9:125,621,034 | G/A | — | uncertain significance |
| rs1588058239 | 9:125,621,067 | C/A | — | uncertain significance |
| rs371486566 | 9:125,621,201 | G/A | — | uncertain significance |
| rs374715315 | 9:125,621,235 | G/C | — | uncertain significance |
| rs915731081 | 9:125,621,366 | G/A | — | uncertain significance |
| rs2792990 | 9:125,621,610 | G/C | intron variant | — |
| rs760677036 | 9:125,622,230 | C/G | — | uncertain significance |
| rs2538192979 | 9:125,622,283 | C/T | — | uncertain significance |
| rs2538193071 | 9:125,622,305 | G/C | — | uncertain significance |
| rs200964914 | 9:125,622,311 | T/G | — | uncertain significance |
| rs768692756 | 9:125,622,312 | T/A | — | uncertain significance |
| rs1269446253 | 9:125,622,391 | T/C | — | uncertain significance |
| rs117294809 | 9:125,627,639 | A/C | — | likely benign |
| rs536446038 | 9:125,627,736 | C/T | — | uncertain significance |
| rs1033444443 | 9:125,627,791 | G/C | — | uncertain significance |
| rs138970845 | 9:125,627,910 | T/C | — | uncertain significance |
| rs56340543 | 9:125,637,584 | A/C | — | likely benign |
| rs767566476 | 9:125,642,114 | T/C | — | uncertain significance |
| rs201858192 | 9:125,642,305 | A/C | — | uncertain significance |
| rs1389587314 | 9:125,642,982 | A/C | — | uncertain significance |
| rs2538277816 | 9:125,645,638 | T/C | — | uncertain significance |
| rs2538293751 | 9:125,652,641 | G/A | — | uncertain significance |
| rs2538293884 | 9:125,652,707 | C/T | — | uncertain significance |
| rs777306835 | 9:125,652,815 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.