rs2814944
This is a downstream gene variant variant.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
coronary artery disease
van der Harst P et al. “Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.” Circulation Research 122(3):433-443 (2018)
Allele A
OR 0.05
p 2.0e-11
N 547,261
Large GWAS
high density lipoprotein cholesterol measurement
Teslovich TM et al. “Biological, clinical and population relevance of 95 loci for blood lipids.” Nature 466(7307):707-713 (2010)
Allele A
OR 0.49
p 4.0e-9
N 99,900
Large GWAS
European
bipolar disorder, body mass index
Pisanu C et al. “Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI.” Translational Psychiatry 9(1):315 (2019)
Allele A
OR 0.02
p 4.0e-8
N 373,864
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…