rs28400013

This variant is located in the IZUMO1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cancer biomarker measurement

Jeon S et al. “Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups.” Gigascience 13 (2024)

Allele T

OR 0.43

p 6.0e-37

N 1,920

Large GWAS

East Asian

About IZUMO1

The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008]

View all IZUMO1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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