IZUMO1
izumo sperm-oocyte fusion 1
Summary
The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008]
Known Variants19 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs767034236 | 19:49,244,571 | C/T | — | uncertain significance |
| rs149174447 | 19:49,244,636 | G/A | — | uncertain significance |
| rs145934248 | 19:49,244,660 | G/A | — | uncertain significance |
| rs758063599 | 19:49,244,735 | A/G | — | uncertain significance |
| rs967220957 | 19:49,245,106 | G/A | — | uncertain significance |
| rs772755461 | 19:49,245,153 | G/A | — | uncertain significance |
| rs1231475849 | 19:49,245,175 | A/C | — | uncertain significance |
| rs1413665506 | 19:49,245,187 | T/A | — | uncertain significance |
| rs1341543311 | 19:49,246,732 | G/A | — | uncertain significance |
| rs838147 | 19:49,246,866 | A/T | — | — |
| rs151047643 | 19:49,247,785 | C/T | — | uncertain significance |
| rs838146 | 19:49,248,052 | C/G | — | — |
| rs838145 | 19:49,248,730 | G/A | regulatory region variant | — |
| rs201790934 | 19:49,248,887 | A/G | — | likely benign |
| rs747353047 | 19:49,248,903 | C/T | — | uncertain significance |
| rs377755047 | 19:49,248,972 | G/A | — | uncertain significance |
| rs2033870016 | 19:49,249,107 | G/A | — | uncertain significance |
| rs145144990 | 19:49,249,359 | C/T | downstream gene variant | — |
| rs28400013 | 19:49,250,672 | C/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.