Trait
SNPs associated with cholesterol in large LDL measurement
101 genetic variants across 37 genes have been associated with cholesterol in large LDL measurement in published research. Key genes include ABCA6, ABCG5, ABCG8.
Associated variants101 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1065853 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs429358 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=9.0e-211) | Large GWAS |
| rs62117160 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs7254892 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs581411 | — | GWAS association (p=4.0e-192) | Large GWAS |
| rs747875948 | — | GWAS association (p=8.0e-186) | Large GWAS |
| rs102275 | TMEM258 | GWAS association (p=7.0e-128) | Large GWAS |
| rs12151108 | — | GWAS association (p=2.0e-94) | Large GWAS |
| rs3846662 | HMGCR | GWAS association (p=2.0e-80) | Large GWAS |
| rs562338 | — | GWAS association (p=5.0e-72) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=2.0e-68) | Large GWAS |
| rs58542926 | TM6SF2 | GWAS association (p=3.0e-63) | Large GWAS |
| rs12750160 | USP24 | GWAS association (p=8.0e-50) | Large GWAS |
| rs35980001 | — | GWAS association (p=3.0e-46) | Large GWAS |
| rs597808 | ATXN2 | GWAS association (p=4.0e-45) | Large GWAS |
| rs28601761 | — | GWAS association (p=4.0e-44) | Large GWAS |
| rs11887534 | ABCG5 | GWAS association (p=1.0e-43) | Large GWAS |
| rs2519093 | ABO | GWAS association (p=2.0e-42) | Large GWAS |
| rs557933 | — | GWAS association (p=7.0e-34) | Large GWAS |
| rs9987289 | LOC157273 | GWAS association (p=2.0e-31) | Large GWAS |
| rs11749783 | — | GWAS association (p=7.0e-31) | Large GWAS |
| rs28383323 | — | GWAS association (p=1.0e-30) | Large GWAS |
| rs147711004 | — | GWAS association (p=4.0e-30) | Large GWAS |
| rs964184 | APOA5 | GWAS association (p=3.0e-27) | Large GWAS |
| rs115478735 | ABO | GWAS association (p=5.0e-26) | Large GWAS |
| rs1800961 | HNF4A | GWAS association (p=8.0e-26) | Large GWAS |
| rs118170342 | — | GWAS association (p=1.0e-25) | Large GWAS |
| rs112875651 | — | GWAS association (p=6.0e-25) | Large GWAS |
| rs1260326 | GCKR | GWAS association (p=4.0e-24) | Large GWAS |
| rs34596921 | — | GWAS association (p=6.0e-24) | Large GWAS |
| rs6475606 | CDKN2B-AS1 | GWAS association (p=1.0e-23) | Large GWAS |
| rs12208357 | SLC22A1 | GWAS association (p=3.0e-22) | Large GWAS |
| rs4307732 | — | GWAS association (p=6.0e-22) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=7.0e-22) | Large GWAS |
| rs58198139 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs525028 | — | GWAS association (p=5.0e-20) | Large GWAS |
| rs2866372 | — | GWAS association (p=7.0e-20) | Large GWAS |
| rs2740488 | — | GWAS association (p=4.0e-19) | Large GWAS |
| rs771193934 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs150169808 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs1461729 | LOC157273 | GWAS association (p=2.0e-18) | Large GWAS |
| rs12948394 | — | GWAS association (p=5.0e-18) | Large GWAS |
| rs35081008 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs261290 | — | GWAS association (p=6.0e-17) | Large GWAS |
| rs77542162 | ABCA6 | GWAS association (p=1.0e-15) | Large GWAS |
| rs11099097 | LOC124900725 | GWAS association (p=2.0e-15) | Large GWAS |
| rs838145 | IZUMO1 | GWAS association (p=3.0e-15) | Large GWAS |
| rs11621792 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs4738684 | — | GWAS association (p=7.0e-15) | Large GWAS |
| rs7709540 | CSNK1G3 | GWAS association (p=8.0e-15) | Large GWAS |
| rs201383809 | — | GWAS association (p=9.0e-15) | Large GWAS |
| rs116734477 | ITGA1 | GWAS association (p=1.0e-14) | Large GWAS |
| rs2642438 | MTARC1 | GWAS association (p=1.0e-14) | Large GWAS |
| rs55714927 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs117815533 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs2624847 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs72836561 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs12150378 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs77960347 | LIPG | GWAS association (p=2.0e-13) | Large GWAS |
| rs7898861 | REEP3 | GWAS association (p=2.0e-13) | Large GWAS |
| rs9884390 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs6882345 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs11693150 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs3794695 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs7773004 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs6073958 | — | GWAS association (p=8.0e-13) | Large GWAS |
| rs514230 | LINC01132 | GWAS association (p=1.0e-12) | Large GWAS |
| rs111278137 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs1883711 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs780094 | GCKR | GWAS association (p=2.0e-12) | Large GWAS |
| rs76428106 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs149394327 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs472495 | PCSK9 | GWAS association (p=4.0e-12) | Large GWAS |
| rs10750766 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs1348790 | ACMSD | GWAS association (p=8.0e-12) | Large GWAS |
| rs11206517 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs34071855 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs633695 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs6920309 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs16926246 | HK1 | GWAS association (p=3.0e-11) | Large GWAS |
| rs3822854 | FRK | GWAS association (p=3.0e-11) | Large GWAS |
| rs146606466 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs56325564 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs10832963 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs2427531 | ZGPAT | GWAS association (p=6.0e-11) | Large GWAS |
| rs41279633 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs8191852 | IGF2R | GWAS association (p=6.0e-11) | Large GWAS |
| rs78946096 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs13283282 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs9604463 | GAS6 | GWAS association (p=8.0e-11) | Large GWAS |
| rs4722551 | LOC105375199 | GWAS association (p=8.0e-11) | Large GWAS |
| rs6771073 | LOC107986092 | GWAS association (p=9.0e-11) | Large GWAS |
| rs13108218 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs80261410 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs73013176 | SMARCA4 | GWAS association (p=1.0e-10) | Large GWAS |
| rs150474434 | INSIG2 | GWAS association (p=2.0e-10) | Large GWAS |
| rs2268702 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs140145058 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs11991231 | — | GWAS association (p=3.0e-30) | Large GWAS |
Showing the top 100 of 101 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.