rs12750160
This is a intron variant variant in the USP24 gene.
▶GWAS Catalog Trait Associations (100)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (100)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
intermediate density lipoprotein measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.16
p 7.0e-62
N 450,015
Large GWAS
multi-ancestry
cholesteryl esters in medium VLDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.16
p 1.0e-61
N 450,015
Large GWAS
multi-ancestry
phospholipids in IDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.16
p 1.0e-60
N 450,015
Large GWAS
multi-ancestry
free cholesterol in IDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.15
p 3.0e-58
N 450,015
Large GWAS
multi-ancestry
total lipids in IDL
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.15
p 6.0e-58
N 450,015
Large GWAS
multi-ancestry
cholesterol in IDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.15
p 1.0e-57
N 450,015
Large GWAS
multi-ancestry
cholesteryl ester measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.15
p 2.0e-57
N 450,015
Large GWAS
multi-ancestry
cholesteryl esters in IDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.15
p 2.0e-56
N 450,015
Large GWAS
multi-ancestry
free cholesterol in small LDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.15
p 2.0e-56
N 450,015
Large GWAS
multi-ancestry
free cholesterol in large LDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.15
p 1.0e-55
N 450,015
Large GWAS
multi-ancestry
About USP24
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
View all USP24 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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