Trait
SNPs associated with free cholesterol in large LDL measurement
158 genetic variants across 55 genes have been associated with free cholesterol in large LDL measurement in published research. Key genes include ABCA6, ABCB11, ABCG5.
Associated variants158 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1065853 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs7412 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs429358 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=5.0e-220) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=3.0e-217) | Large GWAS |
| rs747875948 | — | GWAS association (p=7.0e-217) | Large GWAS |
| rs6511720 | LDLR | GWAS association (p=2.0e-211) | Large GWAS |
| rs646776 | CELSR2 | GWAS association (p=2.0e-206) | Large GWAS |
| rs62117160 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs7254892 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs581411 | — | GWAS association (p=1.0e-180) | Large GWAS |
| rs102275 | TMEM258 | GWAS association (p=2.0e-178) | Large GWAS |
| rs563290 | — | GWAS association (p=1.0e-145) | Large GWAS |
| rs12151108 | — | GWAS association (p=3.0e-100) | Large GWAS |
| rs3846662 | HMGCR | GWAS association (p=4.0e-90) | Large GWAS |
| rs12916 | HMGCR | GWAS association (p=4.0e-83) | Large GWAS |
| rs325 | LPL | GWAS association (p=1.0e-74) | Large GWAS |
| rs562338 | — | GWAS association (p=5.0e-66) | Large GWAS |
| rs261291 | — | GWAS association (p=1.0e-62) | Large GWAS |
| rs174574 | FADS2 | GWAS association (p=9.0e-62) | Large GWAS |
| rs12750160 | USP24 | GWAS association (p=1.0e-55) | Large GWAS |
| rs2519093 | ABO | GWAS association (p=2.0e-50) | Large GWAS |
| rs11887534 | ABCG5 | GWAS association (p=3.0e-49) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=1.0e-48) | Large GWAS |
| rs597808 | ATXN2 | GWAS association (p=5.0e-48) | Large GWAS |
| rs635634 | — | GWAS association (p=2.0e-47) | Large GWAS |
| rs58542926 | TM6SF2 | GWAS association (p=2.0e-43) | Large GWAS |
| rs181948526 | — | GWAS association (p=2.0e-40) | Large GWAS |
| rs35980001 | — | GWAS association (p=7.0e-35) | Large GWAS |
| rs147711004 | — | GWAS association (p=1.0e-33) | Large GWAS |
| rs557933 | — | GWAS association (p=1.0e-32) | Large GWAS |
| rs11749783 | — | GWAS association (p=2.0e-32) | Large GWAS |
| rs7924036 | — | GWAS association (p=4.0e-31) | Large GWAS |
| rs55925606 | — | GWAS association (p=6.0e-31) | Large GWAS |
| rs9987289 | LOC157273 | GWAS association (p=9.0e-30) | Large GWAS |
| rs73001065 | — | GWAS association (p=6.0e-29) | Large GWAS |
| rs72836561 | — | GWAS association (p=8.0e-29) | Large GWAS |
| rs1800961 | HNF4A | GWAS association (p=9.0e-29) | Large GWAS |
| rs115478735 | ABO | GWAS association (p=1.0e-28) | Large GWAS |
| rs117113213 | — | GWAS association (p=3.0e-27) | Large GWAS |
| rs77542162 | ABCA6 | GWAS association (p=3.0e-25) | Large GWAS |
| rs531501453 | — | GWAS association (p=2.0e-24) | Large GWAS |
| rs118170342 | — | GWAS association (p=4.0e-24) | Large GWAS |
| rs4307732 | — | GWAS association (p=2.0e-23) | Large GWAS |
| rs2618568 | — | GWAS association (p=4.0e-23) | Large GWAS |
| rs771193934 | — | GWAS association (p=9.0e-23) | Large GWAS |
| rs6475606 | CDKN2B-AS1 | GWAS association (p=1.0e-22) | Large GWAS |
| rs496800 | LOC124904556 | GWAS association (p=2.0e-22) | Large GWAS |
| rs73066485 | — | GWAS association (p=2.0e-22) | Large GWAS |
| rs12445401 | — | GWAS association (p=3.0e-22) | Large GWAS |
| rs2642438 | MTARC1 | GWAS association (p=4.0e-22) | Large GWAS |
| rs12948394 | — | GWAS association (p=6.0e-22) | Large GWAS |
| rs17411113 | — | GWAS association (p=4.0e-21) | Large GWAS |
| rs149394327 | — | GWAS association (p=6.0e-20) | Large GWAS |
| rs1461729 | LOC157273 | GWAS association (p=1.0e-19) | Large GWAS |
| rs13284054 | — | GWAS association (p=5.0e-19) | Large GWAS |
| rs4722551 | LOC105375199 | GWAS association (p=6.0e-19) | Large GWAS |
| rs55696093 | — | GWAS association (p=9.0e-19) | Large GWAS |
| rs41279633 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs28929474 | SERPINA1 | GWAS association (p=2.0e-18) | Large GWAS |
| rs34060476 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs1399623 | — | GWAS association (p=3.0e-18) | Large GWAS |
| rs28601761 | — | GWAS association (p=3.0e-18) | Large GWAS |
| rs2740488 | — | GWAS association (p=4.0e-18) | Large GWAS |
| rs920811 | IGF2R | GWAS association (p=7.0e-18) | Large GWAS |
| rs12150378 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs2126259 | LOC157273 | GWAS association (p=2.0e-17) | Large GWAS |
| rs35081008 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs2866372 | — | GWAS association (p=5.0e-17) | Large GWAS |
| rs7776156 | — | GWAS association (p=8.0e-17) | Large GWAS |
| rs2792751 | GPAM | GWAS association (p=1.0e-16) | Large GWAS |
| rs4495740 | DOCK7 | GWAS association (p=1.0e-16) | Large GWAS |
| rs10750766 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs55730499 | LPA | GWAS association (p=4.0e-16) | Large GWAS |
| rs11636952 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs2244608 | HNF1A | GWAS association (p=1.0e-15) | Large GWAS |
| rs6699113 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs79598313 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs6882345 | — | GWAS association (p=3.0e-15) | Large GWAS |
| rs3184504 | SH2B3 | GWAS association (p=3.0e-15) | Large GWAS |
| rs4794048 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs1801689 | APOH | GWAS association (p=1.0e-14) | Large GWAS |
| rs201383809 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs2624847 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs11099097 | LOC124900725 | GWAS association (p=2.0e-14) | Large GWAS |
| rs7773004 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs76970536 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs17725246 | — | GWAS association (p=8.0e-14) | Large GWAS |
| rs11601507 | — | GWAS association (p=8.0e-14) | Large GWAS |
| rs111278137 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs7709540 | CSNK1G3 | GWAS association (p=1.0e-13) | Large GWAS |
| rs116734477 | ITGA1 | GWAS association (p=2.0e-13) | Large GWAS |
| rs1169289 | HNF1A | GWAS association (p=2.0e-13) | Large GWAS |
| rs472495 | PCSK9 | GWAS association (p=2.0e-13) | Large GWAS |
| rs55714927 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs77960347 | LIPG | GWAS association (p=2.0e-13) | Large GWAS |
| rs10832954 | SPTY2D1 | GWAS association (p=4.0e-13) | Large GWAS |
| rs112875651 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs4738684 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs6920309 | — | GWAS association (p=8.0e-13) | Large GWAS |
Showing the top 100 of 158 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.