SPTY2D1
SPT2 chromatin protein domain containing 1
Summary
Enables DNA binding activity; histone binding activity; and histone chaperone activity. Involved in heterochromatin formation; nucleosome assembly; and regulation of DNA-templated transcription. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants43 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs147336850 | 11:18,631,412 | C/T | — | uncertain significance |
| rs754368080 | 11:18,631,413 | G/A | — | uncertain significance |
| rs148126716 | 11:18,631,427 | T/C | — | uncertain significance |
| rs10128711 | 11:18,632,984 | T/A | — | — |
| rs2495402831 | 11:18,633,889 | T/C | — | uncertain significance |
| rs768279652 | 11:18,633,970 | C/T | — | uncertain significance |
| rs769366280 | 11:18,633,978 | T/C | — | uncertain significance |
| rs556550699 | 11:18,634,025 | C/A | — | uncertain significance |
| rs1565158140 | 11:18,634,033 | G/A | — | uncertain significance |
| rs747165773 | 11:18,636,208 | A/T | — | uncertain significance |
| rs907931299 | 11:18,636,250 | A/T | — | uncertain significance |
| rs2495406848 | 11:18,636,316 | G/A | — | uncertain significance |
| rs375716843 | 11:18,636,352 | C/T | — | uncertain significance |
| rs200291042 | 11:18,636,391 | C/T | — | uncertain significance |
| rs150441805 | 11:18,636,407 | G/A | — | uncertain significance |
| rs199827890 | 11:18,636,421 | C/T | — | uncertain significance |
| rs199738421 | 11:18,636,425 | C/G | — | uncertain significance |
| rs750127389 | 11:18,636,497 | A/G | — | uncertain significance |
| rs2495407397 | 11:18,636,505 | G/C | — | uncertain significance |
| rs569387737 | 11:18,636,547 | G/C | — | uncertain significance |
| rs367661545 | 11:18,636,554 | T/C | — | uncertain significance |
| rs2495407640 | 11:18,636,631 | G/A | — | uncertain significance |
| rs1291147975 | 11:18,636,754 | A/T | — | uncertain significance |
| rs777519672 | 11:18,636,865 | G/A | — | uncertain significance |
| rs1234970011 | 11:18,636,883 | C/A | — | uncertain significance |
| rs150414163 | 11:18,636,919 | C/T | — | uncertain significance |
| rs1332101506 | 11:18,637,133 | T/G | — | uncertain significance |
| rs777416917 | 11:18,637,207 | C/T | — | uncertain significance |
| rs779603459 | 11:18,637,226 | C/T | — | uncertain significance |
| rs778881481 | 11:18,637,299 | C/G | — | uncertain significance |
| rs756851199 | 11:18,637,366 | A/G | — | uncertain significance |
| rs944188873 | 11:18,637,393 | T/C | — | uncertain significance |
| rs1234300898 | 11:18,637,447 | A/G | — | uncertain significance |
| rs117446236 | 11:18,637,520 | T/C | — | likely benign |
| rs776637522 | 11:18,637,627 | C/T | — | uncertain significance |
| rs200478855 | 11:18,638,427 | C/T | — | likely benign |
| rs909701436 | 11:18,638,460 | G/T | — | uncertain significance |
| rs777219845 | 11:18,638,502 | T/C | — | uncertain significance |
| rs10500834 | 11:18,638,712 | A/C | — | — |
| rs11024735 | 11:18,639,167 | C/G | — | — |
| rs10832954 | 11:18,643,559 | G/T | — | — |
| rs151115079 | 11:18,655,741 | T/C | — | likely benign |
| rs7943121 | 11:18,656,062 | G/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.