Trait
SNPs associated with free cholesterol in LDL measurement
97 genetic variants across 30 genes have been associated with free cholesterol in LDL measurement in published research. Key genes include ABCA6, ABCG5, ABCG8.
Associated variants97 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs429358 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs1065853 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=3.0e-236) | Large GWAS |
| rs747875948 | — | GWAS association (p=1.0e-212) | Large GWAS |
| rs62117160 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs7254892 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs581411 | — | GWAS association (p=2.0e-187) | Large GWAS |
| rs102275 | TMEM258 | GWAS association (p=2.0e-156) | Large GWAS |
| rs12151108 | — | GWAS association (p=5.0e-100) | Large GWAS |
| rs3846662 | HMGCR | GWAS association (p=9.0e-87) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=5.0e-76) | Large GWAS |
| rs562338 | — | GWAS association (p=3.0e-68) | Large GWAS |
| rs325 | LPL | GWAS association (p=6.0e-56) | Large GWAS |
| rs12750160 | USP24 | GWAS association (p=7.0e-55) | Large GWAS |
| rs2519093 | ABO | GWAS association (p=4.0e-49) | Large GWAS |
| rs11887534 | ABCG5 | GWAS association (p=5.0e-48) | Large GWAS |
| rs597808 | ATXN2 | GWAS association (p=8.0e-47) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=2.0e-46) | Large GWAS |
| rs58542926 | TM6SF2 | GWAS association (p=7.0e-46) | Large GWAS |
| rs964184 | APOA5 | GWAS association (p=8.0e-44) | Large GWAS |
| rs147711004 | — | GWAS association (p=2.0e-36) | Large GWAS |
| rs55925606 | — | GWAS association (p=1.0e-33) | Large GWAS |
| rs557933 | — | GWAS association (p=1.0e-31) | Large GWAS |
| rs11749783 | — | GWAS association (p=2.0e-31) | Large GWAS |
| rs9987289 | LOC157273 | GWAS association (p=1.0e-28) | Large GWAS |
| rs115478735 | ABO | GWAS association (p=3.0e-28) | Large GWAS |
| rs4307732 | — | GWAS association (p=3.0e-26) | Large GWAS |
| rs118170342 | — | GWAS association (p=8.0e-26) | Large GWAS |
| rs1800961 | HNF4A | GWAS association (p=4.0e-25) | Large GWAS |
| rs531501453 | — | GWAS association (p=1.0e-24) | Large GWAS |
| rs7924036 | — | GWAS association (p=5.0e-24) | Large GWAS |
| rs771193934 | — | GWAS association (p=1.0e-23) | Large GWAS |
| rs34596921 | — | GWAS association (p=2.0e-23) | Large GWAS |
| rs6475606 | CDKN2B-AS1 | GWAS association (p=8.0e-23) | Large GWAS |
| rs72836561 | — | GWAS association (p=3.0e-21) | Large GWAS |
| rs12948394 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs2866372 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs1461729 | LOC157273 | GWAS association (p=2.0e-18) | Large GWAS |
| rs55696093 | — | GWAS association (p=3.0e-18) | Large GWAS |
| rs920811 | IGF2R | GWAS association (p=3.0e-18) | Large GWAS |
| rs4722551 | LOC105375199 | GWAS association (p=3.0e-18) | Large GWAS |
| rs77542162 | ABCA6 | GWAS association (p=6.0e-18) | Large GWAS |
| rs149394327 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs35081008 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs2642438 | MTARC1 | GWAS association (p=1.0e-16) | Large GWAS |
| rs12150378 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs17411113 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs55714927 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs116734477 | ITGA1 | GWAS association (p=5.0e-16) | Large GWAS |
| rs6073958 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs10750766 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs13284054 | — | GWAS association (p=7.0e-15) | Large GWAS |
| rs7773004 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs11099097 | LOC124900725 | GWAS association (p=1.0e-14) | Large GWAS |
| rs11636952 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs112875651 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs111278137 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs11621792 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs1399623 | — | GWAS association (p=7.0e-14) | Large GWAS |
| rs7709540 | CSNK1G3 | GWAS association (p=8.0e-14) | Large GWAS |
| rs201383809 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs2624847 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs472495 | PCSK9 | GWAS association (p=2.0e-13) | Large GWAS |
| rs765974791 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs41279633 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs58198139 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs6920309 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs10448340 | — | GWAS association (p=9.0e-13) | Large GWAS |
| rs11206517 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs514230 | LINC01132 | GWAS association (p=5.0e-12) | Large GWAS |
| rs12452315 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs146606466 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs13283282 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs76428106 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs117793008 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs4738684 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs34042070 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs838145 | IZUMO1 | GWAS association (p=2.0e-11) | Large GWAS |
| rs4954192 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs2427531 | ZGPAT | GWAS association (p=4.0e-11) | Large GWAS |
| rs2792751 | GPAM | GWAS association (p=4.0e-11) | Large GWAS |
| rs1883711 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs78946096 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs73455634 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs11693150 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs16926246 | HK1 | GWAS association (p=6.0e-11) | Large GWAS |
| rs73013176 | SMARCA4 | GWAS association (p=6.0e-11) | Large GWAS |
| rs150474434 | INSIG2 | GWAS association (p=8.0e-11) | Large GWAS |
| rs9811074 | — | GWAS association (p=8.0e-11) | Large GWAS |
| rs9837622 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs2268702 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs34071855 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs3768321 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs9669354 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs6882345 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs5817082 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs11991231 | — | GWAS association (p=2.0e-57) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.