rs9669354

GWAS Catalog Trait Associations (16)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

total cholesterol measurement

Allele T
OR 0.02
p 3.0e-17
N 394,642
Large GWAS
European
Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 6.0e-11
N 450,015
Large GWAS
multi-ancestry

low density lipoprotein cholesterol measurement

Allele T
OR 0.02
p 5.0e-17
N 928,679
Large GWAS
multi-ancestry
Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele T
OR 0.01
p 2.0e-9
N 361,194
Large GWAS
European

sphingomyelin measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 2.0e-13
N 450,015
Large GWAS
multi-ancestry

free cholesterol in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 6.0e-12
N 450,015
Large GWAS
multi-ancestry

free cholesterol in large LDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 2.0e-11
N 450,015
Large GWAS
multi-ancestry

esterified cholesterol measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 2.0e-11
N 450,015
Large GWAS
multi-ancestry

cholesterol in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 5.0e-11
N 450,015
Large GWAS
multi-ancestry

phospholipids in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 7.0e-11
N 450,015
Large GWAS
multi-ancestry

cholesteryl esters in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 1.0e-10
N 450,015
Large GWAS
multi-ancestry

cholesteryl esters in medium VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 1.0e-10
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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