rs28403275
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
pelvic organ prolapse
Matsunami M et al. “Genome-wide association studies for pelvic organ prolapse in the Japanese population.” Communications Biology 7(1):1188 (2024)
Allele C
OR 1.12
p 2.0e-23
N 651,773
Large GWAS
multi-ancestry
Pujol-Gualdo N et al. “Advancing our understanding of genetic risk factors and potential personalized strategies for pelvic organ prolapse.” Nature Communications 13(1):3584 (2022)
Allele C
OR 1.12
p 2.0e-22
N 574,377
Large GWAS
European
uterine prolapse
Pujol Gualdo N et al. “Atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses.” Nature Medicine 31(5):1626-1634 (2025)
Allele G
OR 0.89
p 2.0e-15
N 234,621
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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