Trait
SNPs associated with Pelvic Organ Prolapse
43 genetic variants across 9 genes have been associated with Pelvic Organ Prolapse in published research. Key genes include DVL2, EFEMP1, GREM1.
Associated variants43 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs3820282 | WNT4 | GWAS association (p=4.0e-31) | Major Consortium Study |
| rs9306894 | — | GWAS association (p=5.0e-26) | Major Consortium Study |
| rs1247943 | — | GWAS association (p=5.0e-22) | Major Consortium Study |
| rs12325192 | — | GWAS association (p=1.0e-21) | Major Consortium Study |
| rs7682992 | — | GWAS association (p=5.0e-16) | Major Consortium Study |
| rs3791675 | EFEMP1 | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs72624976 | IMPDH1 | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs1430191 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs28403275 | — | GWAS association (p=2.0e-23) | Large GWAS |
| rs10219425 | — | GWAS association (p=5.0e-18) | Large GWAS |
| rs11899888 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs11031796 | WT1-AS | GWAS association (p=2.0e-15) | Large GWAS |
| rs2267372 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs1802575 | EFEMP1 | GWAS association (p=1.0e-14) | Large GWAS |
| rs235929 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs4944936 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs4779863 | KLF13 | GWAS association (p=9.0e-12) | Large GWAS |
| rs251217 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs4779517 | KLF13 | GWAS association (p=1.0e-11) | Large GWAS |
| rs4331788 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs42400 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs58170120 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs10013769 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs9855015 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs1544637 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs12314243 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs72839768 | DVL2 | GWAS association (p=5.0e-09) | Large GWAS |
| rs6484161 | SBF2 | GWAS association (p=6.0e-09) | Large GWAS |
| rs1874008 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs10742277 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs2646117 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs12915554 | GREM1 | GWAS association (p=9.0e-09) | Large GWAS |
| rs6502193 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs201194999 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs10810888 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs73197353 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs74794749 | SBF2 | GWAS association (p=2.0e-08) | Large GWAS |
| rs35166569 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs1493202 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs10762631 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs4886778 | LOXL1 | GWAS association (p=4.0e-08) | Large GWAS |
| rs7072877 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs77648136 | — | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.