rs28457693

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

birth weight

Warrington NM et al. “Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.” Nature Genetics 51(5):804-814 (2019)

Allele G

OR 0.04

p 1.0e-25

N 321,223

Large GWAS

multi-ancestry

serum alanine aminotransferase amount

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele A

OR 0.02

p 1.0e-15

N 928,679

Large GWAS

multi-ancestry

birth weight, parental genotype effect measurement

Warrington NM et al. “Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.” Nature Genetics 51(5):804-814 (2019)

Allele G

OR 0.03

p 4.0e-9

N 230,069

Large GWAS

European

body mass index

Helgeland Ø et al. “Characterization of the genetic architecture of infant and early childhood body mass index.” Nature Metabolism 4(3):344-358 (2022)

Allele A

OR 0.07

p 2.0e-8

N 11,095

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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