rs2957468
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
systolic blood pressure
Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)
Allele G
OR 0.20
p 7.0e-15
N 1,028,980
Large GWAS
multi-ancestry
Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele G
OR 0.01
p 7.0e-14
N 1,212,859
Large GWAS
European
diastolic blood pressure
Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)
Allele G
OR 0.12
p 8.0e-14
N 1,028,980
Large GWAS
multi-ancestry
Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele G
OR 0.01
p 5.0e-13
N 1,212,859
Large GWAS
European
schizophrenia, estrogen-receptor positive breast cancer
Tang M et al. “Epidemiological and Genetic Analyses of Schizophrenia and Breast Cancer.” Schizophrenia Bulletin 50(2):317-326 (2024)
Allele A
OR —
p 2.0e-13
N 306,119
Large GWAS
European
schizophrenia, breast carcinoma
Tang M et al. “Epidemiological and Genetic Analyses of Schizophrenia and Breast Cancer.” Schizophrenia Bulletin 50(2):317-326 (2024)
Allele A
OR —
p 4.0e-12
N 377,817
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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