rs296384

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Glycochenodeoxycholate sulfate measurement

Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)

Allele G

OR 0.33

p 4.0e-57

N 8,809

Large GWAS

European

pregnanediol-3-glucuronide measurement

Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)

Allele T

OR 0.12

p 2.0e-18

N 14,296

Large GWAS

European

Intrahepatic cholestasis of pregnancy

Dixon PH et al. “GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.” Nature Communications 13(1):4840 (2022)

Allele T

OR 1.46

p 3.0e-10

N 154,780

Meta-analysisLarge GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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