Trait

SNPs associated with Intrahepatic cholestasis of pregnancy

11 genetic variants across 5 genes have been associated with Intrahepatic cholestasis of pregnancy in published research. Key genes include ABCG8, GCKR, HNF4A.

Associated variants11 total

rsidGeneEffectEvidence
rs4148211ABCG8GWAS association (p=2.0e-33)Meta-analysis
rs28929474SERPINA1GWAS association (p=1.0e-28)Meta-analysis
rs10107182GWAS association (p=2.0e-19)Meta-analysis
rs5885586GWAS association (p=8.0e-17)Meta-analysis
rs1260326GCKRGWAS association (p=7.0e-16)Meta-analysis
rs66927685GWAS association (p=8.0e-16)Meta-analysis
rs2251250GWAS association (p=1.0e-10)Meta-analysis
rs296384GWAS association (p=3.0e-10)Meta-analysis
rs1800961HNF4AGWAS association (p=3.0e-10)Meta-analysis
rs34491636GWAS association (p=3.0e-09)Meta-analysis
rs13146355SHROOM3GWAS association (p=2.0e-08)Meta-analysis

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

Intrahepatic cholestasis of pregnancy — SNPs & genetic associations — Gene Wizard