rs2967668
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Alzheimer disease, family history of Alzheimer’s disease
Jansen IE et al. “Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.” Nature Genetics 51(3):404-413 (2019)
Allele G
OR 10.30
p 7.0e-25
N 455,258
Meta-analysisLarge GWAS
European
Alzheimer disease
Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele G
OR 0.03
p 2.0e-24
N 640,258
Large GWAS
European
Lo MT et al. “Identification of genetic heterogeneity of Alzheimer's disease across age.” Neurobiology of Aging 84:243.e1-243.e9 (2019)
Allele G
OR 1.41
p 3.0e-11
N 14,895
Large GWAS
European
Wang H et al. “Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes.” Frontiers in Aging Neuroscience 13:674318 (2021)
Allele G
OR 0.72
p 2.0e-9
N 12,772
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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