rs3104767
This variant is located in the CASC16 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
restless legs syndrome
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.13
p 6.0e-31
N 623,801
Major Consortium StudyLarge GWAS
multi-ancestry
Tilch E et al. “ExomeChip-based rare variant association study in restless legs syndrome.” Sleep Medicine 94:26-30 (2022)
Allele G
OR 1.34
p 4.0e-16
N 9,012
Large GWAS
European
Winkelmann J et al. “Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.” Plos Genetics 7(7):e1002171 (2011)
Allele G
OR 1.35
p 9.0e-19
N 2,448
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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