rs3138505

This variant is located in the GADD45G gene.

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ClinVar annotation

Benign
2 submitters

GADD45G-related disorder; Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney; Gastric cancer; Cholangiocarcinoma; Lung cancer; Uterine carcinosarcoma; Hepatocellular carcinoma; Cervical cancer

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About GADD45G

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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