rs34174712

This variant is located in the ING5 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

C-X-C motif chemokine 5 measurement

Allele C
OR 0.04
p 2.0e-15
N 47,745
Large GWAS
European

About ING5

This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016]

View all ING5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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