rs34560261

GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

poly(U)-specific endoribonuclease measurement

Allele T
OR 0.08
p 5.0e-41
N 47,745
Large GWAS
European

acne

Mitchell BL et al. Genome-wide association meta-analysis identifies 29 new acne susceptibility loci. Nature Communications 13(1):702 (2022)
Allele C
OR 1.25
p 3.0e-35
N 615,396
Meta-analysisLarge GWAS
European
Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.20
p 3.0e-11
N 442,965
Major Consortium StudyLarge GWAS
European
Teder-Laving M et al. Genome-wide meta-analysis identifies novel loci conferring risk of acne vulgaris. European Journal of Human Genetics : Ejhg 32(9):1136-1143 (2024)
Allele C
OR 1.16
p 1.0e-28
N 399,413
Meta-analysisLarge GWAS
European
Allele C
OR 1.32
p 6.0e-15
N 26,722
Meta-analysisLarge GWAS
European

seborrheic keratosis

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.08
p 2.0e-22
N 392,469
Major Consortium StudyLarge GWAS
European

level of serine protease inhibitor Kazal-type 5 in blood

Allele T
OR 0.06
p 2.0e-20
N 47,745
Large GWAS
European

interleukin 18 measurement

Allele T
OR 0.05
p 1.0e-14
N 47,745
Large GWAS
European

galectin-7 measurement

Allele T
OR 0.04
p 2.0e-12
N 47,745
Large GWAS
European

skin disease

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.05
p 5.0e-12
N 397,744
Major Consortium StudyLarge GWAS
European

corneodesmosin measurement

Allele T
OR 0.02
p 7.0e-12
N 47,745
Large GWAS
European

frontal fibrosing alopecia

Allele T
OR 1.52
p 8.0e-10
N 5,161
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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