Trait
SNPs associated with Seborrheic Keratosis
25 genetic variants across 14 genes have been associated with Seborrheic Keratosis in published research. Key genes include DEF8, FLACC1, IRF4.
Associated variants25 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2853672 | TERT | GWAS association (p=1.0e-185) | Major Consortium Study |
| rs12203592 | IRF4 | GWAS association (p=3.0e-158) | Major Consortium Study |
| rs1126809 | TYR | GWAS association (p=6.0e-50) | Major Consortium Study |
| rs9290890 | — | GWAS association (p=2.0e-45) | Major Consortium Study |
| rs6059655 | RALY | GWAS association (p=4.0e-36) | Major Consortium Study |
| rs11217816 | — | GWAS association (p=4.0e-33) | Major Consortium Study |
| rs4268748 | DEF8 | GWAS association (p=3.0e-31) | Major Consortium Study |
| rs7568453 | LINC00486 | GWAS association (p=1.0e-27) | Major Consortium Study |
| rs4776888 | SMAD3 | GWAS association (p=4.0e-23) | Major Consortium Study |
| rs11611584 | — | GWAS association (p=9.0e-23) | Major Consortium Study |
| rs34560261 | — | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs1049207 | — | GWAS association (p=5.0e-22) | Major Consortium Study |
| rs2036204 | — | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs75507031 | FLACC1 | GWAS association (p=9.0e-20) | Major Consortium Study |
| rs2476601 | PTPN22 | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs75596709 | — | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs117744081 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs11170164 | KRT5 | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs9989905 | — | GWAS association (p=5.0e-14) | Major Consortium Study |
| rs1539690 | — | GWAS association (p=8.0e-14) | Major Consortium Study |
| rs12117155 | TUFT1 | GWAS association (p=9.0e-14) | Major Consortium Study |
| rs7040151 | — | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs9815073 | LPP | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs1800407 | OCA2 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs16891982 | SLC45A2 | GWAS association (p=5.0e-72) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.