rs34598464
This variant is located in the NPEPPS gene.
▶ClinVar annotation
not provided; Clear cell carcinoma of kidney; Gastric cancer; Colorectal cancer; Melanoma; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Hepatocellular carcinoma; Lung cancer; Cervical cancer
View on ClinVar →About NPEPPS
This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]
View all NPEPPS variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…