rs352181
This is a intron variant variant in the THSD7B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
substance-related disorder
Lai D et al. “Genome-wide meta-analyses of cross substance use disorders in diverse populations.” Molecular Psychiatry 31(3):1619-1633 (2026)
Allele A
OR 5.54
p 3.0e-8
N 1,458,999
Large GWAS
European
About THSD7B
Predicted to be involved in actin cytoskeleton organization. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all THSD7B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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