rs35225200

This is a intergenic variant variant.

GWAS Catalog Trait Associations (19)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

osteoarthritis

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.10
p 1.0e-26
N 402,508
Major Consortium StudyLarge GWAS
European

docosahexaenoic acid measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.03
p 3.0e-18
N 450,015
Large GWAS
multi-ancestry

Arthralgia

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.07
p 2.0e-17
N 398,498
Major Consortium StudyLarge GWAS
European

degree of unsaturation measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.03
p 5.0e-15
N 450,015
Large GWAS
multi-ancestry
Allele C
OR
p 1.0e-9
N 239,268
Large GWAS
European

triglyceride measurement

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.03
p 5.0e-13
N 455,659
Large GWAS
multi-ancestry

nail disorder

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.09
p 1.0e-11
N 423,754
Major Consortium StudyLarge GWAS
European

fatty acid amount

Allele C
OR
p 3.0e-11
N 128,922
Large GWAS
European

Abnormality of movement

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.07
p 4.0e-11
N 569,666
Major Consortium StudyLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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