rs35267984
This is a intron variant variant in the MED16 gene.
▶GWAS Catalog Trait Associations (57)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (57)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
interleukin-34 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.62
p 2.0e-19
N 10,708
Large GWAS
European
C-C motif chemokine 1 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.62
p 3.0e-19
N 10,708
Large GWAS
European
tumor necrosis factor receptor superfamily member 3 amount
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.62
p 3.0e-19
N 10,708
Large GWAS
European
tropomyosin beta chain measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.62
p 4.0e-19
N 10,708
Large GWAS
European
insulin growth factor-like family member 3 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.62
p 9.0e-19
N 10,708
Large GWAS
European
zinc finger protein 276 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.62
p 1.0e-18
N 10,708
Large GWAS
European
epididymal-specific lipocalin-10 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.61
p 3.0e-18
N 10,708
Large GWAS
European
cyclin-dependent kinase 5:cyclin-dependent kinase 5 activator 1 complex measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.60
p 4.0e-18
N 10,708
Large GWAS
European
desmoglein-1 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.60
p 6.0e-18
N 10,708
Large GWAS
European
kallikrein-12 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.59
p 1.0e-17
N 10,708
Large GWAS
European
About MED16
Enables nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Involved in positive regulation of transcription initiation by RNA polymerase II. Located in nucleus. Part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Jul 2025]
View all MED16 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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