rs35389403

This variant is located in the DKKL1 gene.

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ClinVar annotation

Benign★★★☆
3 submitters2 publications

not provided; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma; Clear cell carcinoma of kidney; Uterine carcinosarcoma

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About DKKL1

The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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