rs367637862
This variant is located in the EIF4G3 gene.
▶ClinVar annotation
About EIF4G3
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
View all EIF4G3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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