rs368705994
This variant is located in the DGCR8 gene.
▶ClinVar annotation
Likely Benign★★★☆
2 submitters2 publicationsAbout DGCR8
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
View all DGCR8 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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