rs371876172
This variant is located in the POLI gene.
▶ClinVar annotation
About POLI
The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017]
View all POLI variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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