rs371968350
This variant is located in the TNS1 gene.
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitter1 publicationAbout TNS1
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
View all TNS1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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