rs373484478
This variant is located in the MAP3K2 gene.
▶ClinVar annotation
About MAP3K2
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008]
View all MAP3K2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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