rs3756838

This is a regulatory region variant variant in the RNASET2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Hashimoto's thyroiditis

White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)

Allele A

OR 0.14

p 3.0e-22

N 1,815,514

Large GWAS

multi-ancestry

About RNASET2

This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]

View all RNASET2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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