Trait
SNPs associated with Hashimoto's thyroiditis
92 genetic variants across 40 genes have been associated with Hashimoto's thyroiditis in published research. Key genes include ADCY7, ARID5B, ATXN2.
Associated variants92 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs6679677 | PHTF1 | GWAS association (p=1.0e-93) | Large GWAS |
| rs9271365 | — | GWAS association (p=3.0e-77) | Large GWAS |
| rs7847663 | PTCSC2 | GWAS association (p=1.0e-50) | Large GWAS |
| rs2476601 | PTPN22 | GWAS association (p=3.0e-45) | Large GWAS |
| rs10739496 | — | GWAS association (p=1.0e-43) | Large GWAS |
| rs11571302 | — | GWAS association (p=5.0e-43) | Large GWAS |
| rs3087243 | CTLA4 | GWAS association (p=9.0e-39) | Large GWAS |
| rs80173139 | VAV3 | GWAS association (p=2.0e-37) | Large GWAS |
| rs7030280 | — | GWAS association (p=6.0e-31) | Large GWAS |
| rs3184504 | SH2B3 | GWAS association (p=1.0e-25) | Large GWAS |
| rs3756838 | RNASET2 | GWAS association (p=3.0e-22) | Large GWAS |
| rs75143612 | PHF20L1 | GWAS association (p=2.0e-19) | Large GWAS |
| rs7073236 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs114322847 | TG | GWAS association (p=1.0e-18) | Large GWAS |
| rs17020139 | VAV3 | GWAS association (p=3.0e-18) | Large GWAS |
| rs71508903 | ARID5B | GWAS association (p=7.0e-17) | Large GWAS |
| rs201758905 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs72928038 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs1993945 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs13098877 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs705704 | RPS26 | GWAS association (p=4.0e-15) | Large GWAS |
| rs661713 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs117295261 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs10168266 | STAT4 | GWAS association (p=9.0e-15) | Large GWAS |
| rs796395 | LINC02869 | GWAS association (p=1.0e-14) | Large GWAS |
| rs706778 | IL2RA | GWAS association (p=1.0e-14) | Large GWAS |
| rs34636506 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs12575636 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs368679067 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs2921055 | LOC107986913 | GWAS association (p=5.0e-13) | Large GWAS |
| rs773111 | RAB5B | GWAS association (p=6.0e-13) | Large GWAS |
| rs229527 | C1QTNF6 | GWAS association (p=7.0e-13) | Large GWAS |
| rs3009947 | — | GWAS association (p=9.0e-13) | Large GWAS |
| rs897586 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs229541 | C1QTNF6 | GWAS association (p=4.0e-12) | Large GWAS |
| rs11052877 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs1534424 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs117877581 | SIK3 | GWAS association (p=2.0e-11) | Large GWAS |
| rs17786733 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs2980767 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs13403150 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs2456451 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs11889341 | STAT4 | GWAS association (p=7.0e-11) | Large GWAS |
| rs9729719 | MTF1 | GWAS association (p=8.0e-11) | Large GWAS |
| rs62116084 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs12635334 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs617051 | RPS6KA4 | GWAS association (p=2.0e-10) | Large GWAS |
| rs757024 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs9277768 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs4683651 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs3775291 | TLR3 | GWAS association (p=6.0e-10) | Large GWAS |
| rs479777 | CCDC88B | GWAS association (p=7.0e-10) | Large GWAS |
| rs11335233 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs10422141 | TICAM1 | GWAS association (p=1.0e-09) | Large GWAS |
| rs9840444 | RETNLB | GWAS association (p=1.0e-09) | Large GWAS |
| rs34046593 | RBPJ | GWAS association (p=1.0e-09) | Large GWAS |
| rs28752787 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs7754251 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs75140957 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs12537 | MTMR3 | GWAS association (p=2.0e-09) | Large GWAS |
| rs9497965 | SASH1 | GWAS association (p=2.0e-09) | Large GWAS |
| rs189919570 | LOC124902436 | GWAS association (p=2.0e-09) | Large GWAS |
| rs10836360 | SLC1A2 | GWAS association (p=2.0e-09) | Large GWAS |
| rs59384702 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs16878091 | LINC02357 | GWAS association (p=2.0e-09) | Large GWAS |
| rs72678531 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs10718028 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs759413942 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs13380830 | RAB5C | GWAS association (p=6.0e-09) | Large GWAS |
| rs11940117 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs4444866 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs11611029 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs28367766 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6679356 | IL12RB2 | GWAS association (p=1.0e-08) | Large GWAS |
| rs8018479 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs12981033 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs10849 | LRRFIP2 | GWAS association (p=2.0e-08) | Large GWAS |
| rs3763591 | CHD7 | GWAS association (p=2.0e-08) | Large GWAS |
| rs377413889 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs2110451 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs527437542 | VPS13B | GWAS association (p=3.0e-08) | Large GWAS |
| rs73069539 | SKAP2 | GWAS association (p=3.0e-08) | Large GWAS |
| rs212399 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs144209445 | LOC105375926 | GWAS association (p=4.0e-08) | Large GWAS |
| rs2282655 | PANX1 | GWAS association (p=4.0e-08) | Large GWAS |
| rs145238913 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs1050979 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs6998901 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs11033048 | SLC1A2 | GWAS association (p=4.0e-08) | Large GWAS |
| rs35776863 | — | GWAS association (p=9.0e-09) | Large GWAS |
| rs7137828 | ATXN2 | GWAS association (p=2.0e-55) | Large GWAS |
| rs78534766 | ADCY7 | GWAS association (p=1.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.