rs705704
This variant is located in the RPS26 gene.
▶GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
type 1 diabetes mellitus
Crouch DJM et al. “Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow-Up Studies.” Genetic Epidemiology 49(1):e22608 (2025)
Allele A
OR 1.22
p 2.0e-37
N 173,981
Large GWAS
European
Thyroid preparation use measurement
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele A
OR 0.07
p 9.0e-16
N 484,308
Large GWAS
multi-ancestry
Hashimoto's thyroiditis
White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)
Allele A
OR 0.10
p 4.0e-15
N 1,815,514
Large GWAS
multi-ancestry
body mass index
Pulit SL et al. “Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.” Human Molecular Genetics 28(1):166-174 (2019)
Allele A
OR 0.01
p 6.0e-15
N 374,756
Meta-analysisLarge GWAS
European
asthma
Ishigaki K et al. “Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.” Nature Genetics 52(7):669-679 (2020)
Allele A
OR 1.14
p 7.0e-10
N 209,808
Large GWAS
East Asian
Cleft palate, cleft lip
Yu Y et al. “Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity.” Nature Communications 8:14364 (2017)
Allele A
OR 1.22
p 1.0e-9
N 6,084
Large GWAS
East Asian
▶ClinVar annotation
Benign★★★☆
2 submitters1 publicationAbout RPS26
This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. Mutations in this gene are found in Diamond-Blackfan anemia 10. There are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Aug 2017]
View all RPS26 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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